Is the new 23andMe v5 chip compatible with Gedmatch?

Question

The answer is no but....

Here is the notice currently on Gedmatch.

Aug 10, 2017 

NOTICE to 23andMe Customers: 23andMe is now using the GSA chip for their new V5 raw DNA file results. This format is not compatible with the regular GEDmatch upload but can be used with the GEDmatch Genesis upload. Use the link in the lower right column of this page. 

edit: Here is an extract from a blogger....

"Because there are so few overlapping markers between the GSA and the OmniExpress this change will also present problems for companies and third-party websites that accept autosomal DNA transfers"

https://cruwys.blogspot.com/2017/08/23andme-launch-new-v5-chip-and-revise.html

Comments

I'm shocked.  Thanks for posting this Ken!

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No. It's not. I emailed this afternoon and heard back from Curtis Rogers, Co-Administrator who wrote, 

"Until we combine Genesis with our primary database you will not be able to get matches with out [sic]  primary database or use the tools on Tier 1. We are working hard to combine the two databases but anticipate it may take a few more months to combine the two databases."

I have also discovered that the GEDmatch Genesis kit numbers are not being accepted here on WikiTree. It throws an error because there are two letters in the beginning instead of one letter and 9 numerals.  Can an admin chime in to indicate if this can or will be rectified soon?

I feel rather cut off on nearly all routes I have attempted to utilize in uploading my kit to do further research.  The only website thus far I have found to work with the v5 chip is promethease.com.

 

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Hi, Anne. A couple of previous threads on the GEDmatch Genesis numbering matter:

https://www.wikitree.com/g2g/422508/someone-update-test-page-allow-entry-gedmatch-kit-for-living

https://www.wikitree.com/g2g/448227/could-wikitree-add-gedmatch-genesis-ids

In the latter, leader Mags Gaulden made a request for the WikiTree coders with the really big brains to put this on their radar for a possible solution. My personal opinion is that there are two factors that may make a fix a bit more complicated than it might seem at a glance.

First is that Genesis is currently a beta service at GEDmatch, and I don't know if anyone knows exactly what that merged database will look like. I believe it's safe to assume that current production GEDmatch kit numbers will not change; but since Genesis is clearly marked as in beta test, those kit numbers well might.

Second, WikiTree has the application interface thing in place with GEDmatch that places a live link back to WikiTree profiles from one-to-many comparisons. I assume that WikiTree passing Genesis kit numbers into this system will cause breakages. And if Genesis data will be merged into the GEDmatch production database, WikiTree building a new, standalone solution for Genesis will likely have a production lifespan of only a few months at best. That possibly means WikiTree would then have to programmatically back-out all the changes to profiles and force folks to enter the new GEDmatch information manually. May be neither inexpensive nor practical. We'll just need to wait and see what develops.

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Here is what gedmatch told me...

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For kits uploaded since April we will have the full dna rather than the dna which matched the template we used.  Older kits will work with the template dna.

In both cases the kit numbers will remain the same (or that is what we are planning).

We are checking for duplicates but will not be able to do that with data that is uploaded directly to genesis and data which was loaded before April.

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All my kits are now in Genisis. If everything goes as planned, I will be using the Genisis format for all my kits and will encourage others to do the same. I am doing this so that all the DNA SNP's will be used in the comparison, not just the template SNP's.

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Thank you for that explanation and information Edison.  I found the additional threads after my post above. I should have searched further prior to posting, hopefully a lesson was learned...

With those discussions and your comments above, it does make perfect sense to keep a beta out of the main and off wikitree due to the rather major differences between them. 

I have a lot of work to do in learning wikitree and sourcing materials.  If I'm lucky, I'll have gotten a good deal done by the time this is all sorted out.  Thanks again.

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If I understand correctly Ken, they/you are saying that all will be well with the exception of the kits loaded to Genesis prior to April 2017 that haven't been reloaded to Genesis since that time?

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Here is my understanding.  The kit numbers will remain the same after the merge. But there are some incentives to reloading the kits.

1. There is or will be a duplication check.  An older kit, (Kits loaded prior to April), will not look like a duplicate when newer kit (Kits loaded after April) are loaded.  

2. Older kits were placed into a template. This seems to mean that some SNP's that were not in the template, were not used.  They will be used if the kits are reloaded. This is reason enough for me to reload all my kits, and use the new format.

I noticed some differences between matches on current gedmatch and that of Genesis, but nothing significant.

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Very good, that's very clear.  Thanks Ken

Answer 1

I understand it is (will be) compatible with GEDmatch's Genesis.