Isabella was born July 6, 1819 to Henry Cogswell and Isabell Ellis. She never married. She is shown as a Philanthropist in the Dictionary of Canadian (more information below). She died in 1874 at Halifax, Nova Scotia.
Sources
Vital statistics of Nova Scotia - birth and death
Novascotiagenealogy.com
Family Search Community Trees Person ID I3248 Family ID 1444
Dictionary of Canadian Biography for Isabella Cogswell Vol. X (1871-1880)
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DNA Connections
It may be possible to confirm family relationships with Isabella by comparing test results with other carriers of her ancestors' mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Isabella: