In William's mother's will which was dated May 13, 1819, she refers to her deceased son. She mentions that he had children. I don't have information on his wife or how many children he had.
Sources
Wanda Richards
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DNA Connections
It may be possible to confirm family relationships with William by comparing test results with other carriers of his ancestors' Y-chromosome or mitochondrial DNA.
Y-chromosome DNA test-takers in his direct paternal line on WikiTree: