Seneca married Rosetta Morilda Myers in 1882 - parents of Ada Bell Adams.
Sources
"United States Census, 1870," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:M6W1-NSL : 12 April 2016), Seneca W Adams in household of Asa Adams, Illinois, United States; citing p. 9, family 63, NARA microfilm publication M593 (Washington D.C.: National Archives and Records Administration, n.d.); FHL microfilm 545,793.
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DNA Connections
It may be possible to confirm family relationships with Seneca by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Seneca: