Lydia is buried at Draper Cemetery in Pulaski County, VA. It appears as though she remained unmarried throughout her life.
Sources
Find A Grave memorial #79531326
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DNA Connections
It may be possible to confirm family relationships with Lydia by comparing test results with other carriers of her ancestors' mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Lydia: