Orpha was born about 1869. She was the daughter of George Denison and Saloma Fenner. She passed away in 1933.
Sources
Indiana, Marriages, 1811-1959, found at FamilySearch.org (Robert E Salyer)
Ohio, County Marriages, 1774-1993 (John Mayer)
U.S., Find A Grave Index, 1600s-Current
Death certificate of Orpha Teressa (Denison) Mayer, Ohio Deaths 1908-1953
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DNA Connections
It may be possible to confirm family relationships with Orpha by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Orpha: