William was born in 1811. William Grizzle passed away in 1893.
Sources
"United States Census, 1850," database with images, FamilySearch (https://www.familysearch.org/ark:/61903/1:1:M8DP-CK8 : 23 December 2020), William H Grizzle, Russell, Russell, Virginia, United States; citing family , NARA microfilm publication (Washington, D.C.: National Archives and Records Administration, n.d.).
Find a Grave, database and images (https://www.findagrave.com/memorial/157451600/william-hensley-grizzle : accessed 05 May 2022), memorial page for William Hensley “Little Billy L.B.” Grizzle (18 Oct 1811–1 Apr 1893), Find a Grave Memorial ID 157451600, citing Grizzle Family1 Cemetery, Castlewood, Russell County, Virginia, USA
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DNA Connections
It may be possible to confirm family relationships with William by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with William: