Thomas, second son of the Irish Quaker linen manufacturer Jacob Hancock, was born on 24 March 1783 in Lisburn, County Antrim. An ambitious young man, he was educated at Ackford, Yorkshire, was apprenticed to a surgeon at Waterford, and graduated M.D. from the University of Edinburgh on 26 June 1809, receiving his licensate from the Royal College of Physicians in London the same year. In 1810, he married Hannah Wakefield Strangman. The association with the ancient Strangman family would be a source of pride for Thomas’ descendants.
Over the next 17 years, Dr. Hancock practiced medicine in London, living in Finsbury Square. He was elected physician to the City and Finsbury dispensaries. A man of extensive reading, he published works on medicine, law and religion, including An Elegy Supposed to be Written on a Field of Battle (1818), The Law of Mercy, a Poetical Essay on the Punishment of Death (1819), Researches into the Laws and Phenomena of Pestilence (1821), Essay on Instinct and its Physical and Moral Relations (1824), The Principles of Peace exemplified in the Conduct of the Society of Friends in Ireland during the Rebellion of the year 1798 (1825), The Laws and Progress of the Epidemic Cholera (1832), and A Defence of the Doctrines of Immediate Revelation and Universal Saving Light (1835).
In 1827, Thomas lost two children, Mary and John, to whooping cough, and the next year his wife Hannah died shortly after giving birth, leaving Thomas with six young children. The newborn, named Hannah Wakefield Hancock in her mother’s memory, was sent off to live with her aunts. Thomas’ eldest daughter Emma, at the age of 14, took charge of raising her younger siblings.
In 1829, shortly after Hannah's death, Thomas moved to Liverpool to open a new medical practice. In a gloomy letter to a friend, he wrote,
Thomas did not prosper in Liverpool; he had to draw upon his savings and give up his carriage to economise. In 1836, he retired to Lisburn, where he lived with his eldest daughter Emma until her death from tuberculosis in 1843. He died of heart disesase in Lisburn on 16 April 1849. In his will, he left his property to his sons, subject to a curious condition:
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