The Mayflower Descendant: a quarterly magazine of Pilgrim genealogy and history, 1899, p. 232 - Eastham and Orleans, Mass., Vital Records: "Isaiah higgins Son of Ebenezor higgins & abigel higgins was born in Eastham the 5 of april 1727"
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DNA Connections
It may be possible to confirm family relationships with Isaiah by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Isaiah: