Descendant of Pilgrim Francis Cooke (1583-1663) via mother Ruth (Cooke) Holmes.
Sources
Vital Records of Kingston Massachusetts to the year 1850, (Boston: New England Historic Genealogical Society, 1911), p. 92 (birth)
Vital Records of Plympton Massachusetts to the year 1850, (Boston: New England Historic Genealogical Society, 1923), p. 332 (marriage); 486 (death and cemetery)
Ralph V. Wood, Jr., comp., Mayflower Families Through Five Generations, Francis Cooke, Volume 12, (Plymouth: General Society of Mayflower Descendants, 2015), p. 452.
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DNA Connections
It may be possible to confirm family relationships with Francis by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
Y-chromosome DNA test-takers in his direct paternal line on WikiTree: