John was born in Lancaster County, Pennsylvania. In 1820 he married Elizabeth Graybill Eshleman. They had at least nine known children, Joseph, Christian, Sussana, Fannie, Catherine, John, Elizabeth, Abraham, and Michael.
Sources
"United States Census, 1870," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:MN3P-81X : 12 April 2016), John N Horst, Maryland, United States; citing p. 22, family 155, NARA microfilm publication M593 (Washington D.C.: National Archives and Records Administration, n.d.); FHL microfilm 552,096.
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DNA Connections
It may be possible to confirm family relationships with John by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with John: