Mary was wed to James Downing on 13 February 1749 in Augusta County, Virginia Colony.
Mary King Downing died in the Colony of Virginia.
Sources
Gedcom from Lorri Carter as given by Eowyn Langholf
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DNA Connections
It may be possible to confirm family relationships with Mary by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Mary: