Her birth occurred in an area in Virginia that became West Virginia in 1863.
Sources
"United States Census, 1850," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:M8DV-QH8 : 9 November 2014), Mary E Lambert in household of Arnold Lambert, Pendleton county, Pendleton, Virginia, United States; citing family 611, NARA microfilm publication M432 (Washington, D.C.: National Archives and Records Administration, n.d.).
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DNA Connections
It may be possible to confirm family relationships with Mary by comparing test results with other carriers of her ancestors' mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Mary: