Mary was born in 1846. She was the daughter of Samuel Ledford and Nancy Miller. She passed away in 1923. Mary never married.
Sources
"United States Census, 1850," database with images, FamilySearch (https://www.familysearch.org/ark:/61903/1:1:M4B7-K8K : 23 December 2020), Mary V Ledford in household of Saml Ledford, Buncombe, North Carolina, United States; citing family , NARA microfilm publication (Washington, D.C.: National Archives and Records Administration, n.d.).
"United States Census, 1880," database with images, FamilySearch (https://www.familysearch.org/ark:/61903/1:1:M6XB-QPK : 14 January 2022), Mary Ledford in household of Sam'l Ledford, Dayton Township, Newton, Missouri, United States; citing enumeration district , sheet , NARA microfilm publication T9 (Washington, D.C.: National Archives and Records Administration, n.d.), FHL microfilm .
Find a Grave, database and images (https://www.findagrave.com/memorial/57483884/mary-estel-ledford : accessed 07 June 2022), memorial page for Mary Estel Ledford (24 Nov 1846–3 Oct 1923), Find a Grave Memorial ID 57483884, citing Cummings Chapel Cemetery, Tiff City, McDonald County, Missouri, USA ; Maintained by Paula Ledford Waller (contributor 47273300) .
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DNA Connections
It may be possible to confirm family relationships with Mary by comparing test results with other carriers of her ancestors' mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Mary: