The date and location of Annie's death is uncertain, but based on the number of her children and their estimated birth dates it is likely to be after 1760.
Sources
↑ "New Hampshire Births and Christenings, 1714-1904," database, FamilySearch: 10 Feb 2018, Annis Locke, 25 Mar 1723; citing Hampton Twp., Rockingham, New Hampshire; FHL microfilm 1,001,013.
↑ 2.02.12.2 Locke, Arthur Horton, A History and Genealogy of Captain John Locke (1627-1696) of Portsmouth and Rye, N.H., and his Descendants; also of Nathaniel Locke of Portsmouth, and a Short Account of the History of the Lockes in England. Rumford Press: Concord NH, 1916. Access online at Archive.org, p. 16 (parents), p. 32 (DOB, marriage, children).
↑ "New Hampshire Marriages, 1720-1920," database, FamilySearch: 10 Feb 2018, John Perkins and Annie Lock, 10 Mar 1748; citing ref Item 7, p.103; FHL microfilm 2,169,156.
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DNA Connections
It may be possible to confirm family relationships with Annis by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Annis: