Lee-o-netto was known throughout Western New York State as an Indian Doctress. She traveled a regular circuit and worked out of hotel lobbies. She specialized in women's ailments. Lee-o-netto provided her services for free and charged for her medicines.
At times she traveled with a showman known as U-ta-wa-un and his Indian Medicine Company. In 1889 they were touring in Vermont.
She practiced medicine from the age of about 25 right up to the year before her death. At the time of death she had a substantial estate, suggesting she was very good at her chosen occupation.
You can view her very impressive stone monuments in the Allegany Cemetery on Find-A-Grave.
Data & Discussion
For a detailed review of records, images, and other items of interest concerning this individual please visit the Dr. Lee-o-netto post on my research blog. I update this post whenever I discover new items.
Leonnetta appears in the 1870 U.S. Census for Rathbone, Steuben Co., NY in the household of Layton Kanistanaux. 
Isaac Kiness (aka Dr. I. J. Kanistanaux) and Leonetto purchase 100 acres in Stockton, Chautauqua Co., NY and build a home in the summer of 1874. They are identified as husband and wife at this time. 
Leonetta has not been found in the 1875 New York State Census.
Mrs. Leonetto appears in the 1880 U.S. Census for Rome, Oneida Co., NY as a widow (but Isaac Kiness is still living!) and Indian Doctress.
Nettie Kineiss married Charles J. Dodge at Kinzua, Warren Co., PA while living in Bradford, McKean Co., PA.