"United States Census, 1850," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:MHJG-MP8 : accessed 11 February 2016), Louisa Simpson in household of Luderick Simpson, Knox county, part of, Knox, Indiana, United States; citing family 174, NARA microfilm publication M432 (Washington, D.C.: National Archives and Records Administration, n.d.).
"United States Census, 1860", database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:M4F2-S1Z : accessed 11 February 2016), Louisa J Simpson in entry for Frederick Simpson, 1860.
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DNA Connections
It may be possible to confirm family relationships with Louisa by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Louisa: