↑ "United States Census, 1860," index, FamilySearch (https://familysearch.org/pal:/MM9.1.1/MD6D-ZZS : accessed 12 March 2015), William Nicholson in household of E P Nicholson, , Henderson, North Carolina, United States; citing p. 193, household ID 1331, NARA microfilm publication M653, National Archives and Records Administration, Washington, D.C.; FHL microfilm 803,901.
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DNA Connections
It may be possible to confirm family relationships with Isaac by comparing test results with other carriers of his ancestors' Y-chromosome or mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Isaac: