According to family history, the Pagans originally came from Scotland to American in 1765. Alexander was a native of Ireland who came to Lancaster, Pennsylvania with his parents and 2 brothers, James and Archibald. They subsequently moved to South Carolina.
Sources
Find A Grave memorial #11197710-Fishing Creek Churchyard, Chester County, South Carolina
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DNA Connections
It may be possible to confirm family relationships with Alexander by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Alexander: