"Virginia, Marriages, 1785-1940," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:XRWS-362 : accessed 22 July 2015), Arthur Reid in entry for John M. Black and Isabella Reid, 25 Aug 1859; citing Washington Co., Virginia, reference Page 29; FHL microfilm 34,389.
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DNA Connections
It may be possible to confirm family relationships with Isabella by comparing test results with other carriers of her ancestors' mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Isabella: