Hiram may have taken his family to Iowa with his parents and siblings. This 1850 Census record might be them:
"United States Census, 1850," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:MZ46-TTK : 12 April 2016), Hiram B Scott, Rome, Jones, Iowa, United States; citing family 739, NARA microfilm publication M432 (Washington, D.C.: National Archives and Records Administration, n.d.).
Sources
"Ohio Marriages, 1800-1958," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:XDZJ-MXV : 10 February 2018), Hiram B. Scott and Elizabeth Gilbert, 12 Jan 1843; citing Columbiana Co., Ohio, reference 2:3WT2KFF; FHL microfilm 927,766.
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DNA Connections
It may be possible to confirm family relationships with Hiram by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Hiram:
good catch - was a bit of a typo, but all fixed now