Isiah was born about 1746. Isiah Tuttle ... He passed away about 1820.
Sources
Tuttle, Alva M., Compiler. Tuttle Tuthill Lines in America. Columbus, Ohio: Printed by Estel Printing Service, 1968. p. 274.
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DNA Connections
It may be possible to confirm family relationships with Isiah by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Isiah: