Ann was born in about 1812 (aged 38 in the US census 1850).
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Sources
"England Marriages, 1538–1973 ," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:NJJ3-M82 : 10 February 2018), Isaac Blackwell and Ann Rose, 16 Jun 1830; citing Rotherham, York, England, reference 87, index based upon data collected by the Genealogical Society of Utah, Salt Lake City; FHL microfilm 919,317.
"England and Wales Census, 1841," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:MQ5H-G9Q : 23 May 2019), Anne Blackwell in household of Isaac Blackwell, Sheffield, Yorkshire, England, United Kingdom; from "1841 England, Scotland and Wales census," database and images, findmypast (http://www.findmypast.com : n.d.); citing PRO HO 107, The National Archives, Kew, Surrey.
"United States Census, 1850," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:MCY5-GBN : 12 April 2016), Isaac Blackwell, Brooklyn, ward 11, Kings, New York, United States; citing family 1184, NARA microfilm publication M432 (Washington, D.C.: National Archives and Records Administration, n.d.).
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DNA Connections
It may be possible to confirm family relationships with Ann by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Ann: