After marriage to Marinda (Fox) Ewell, they moved to Keyesville, Missouri in 1834 and returned to Laurel County Kentucky in 1845.
Sources
"Watkins Family History" researched by Myrtle Weaver Felts, Corbin, Kentucky in 1966, and up-dated by Fred F. Keene 7-19-1995 (and later up-dated by Mark A. Watkins).
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DNA Connections
It may be possible to confirm family relationships with Wiley by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Wiley: