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Sources
"United States Census, 1850," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:MDZN-MB2 : 12 April 2016), John Wheeler, Neosho, Newton, Missouri, United States; citing family 550, NARA microfilm publication M432 (Washington, D.C.: National Archives and Records Administration, n.d.).
↑ First-hand information as remembered by Langley Howse, Sunday, August 3, 2014. Replace this citation if there is another source.
Ancestry.com: "Tennessee, U.S., Compiled Marriages, 1784-1825," John Wheeler and Sarah Sanders, 2 April 1818, place Knox County, Tennessee as per Ancestry source data: Ancestry.com. Tennessee, U.S., Marriage Records, 1780-2002 [database on-line]. Lehi, UT, USA: Ancestry.com Operations Inc, 2008.
Original data: Tennessee State Marriages, 1780-2002. Nashville, TN, USA: Tennessee State Library and Archives. Microfilm.
Wheeler-6370 was created by Jim Dorrough through the import of JAMES DORROUGH_2014-07-03_01.ged on Jul 12, 2014.
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DNA Connections
It may be possible to confirm family relationships with John by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
Y-chromosome DNA test-takers in his direct paternal line on WikiTree:
Reginald Wheeler :
AncestryDNA Paternal Lineage (discontinued) 46 markers, haplogroup I-1, Ancestry member rwheeler90 +
Family Tree DNA Y-DNA Test 700 markers, haplogroup I-FT351547, FTDNA kit #271612
It is likely that these autosomal DNA test-takers will share some percentage of DNA with John: