Various examples from Wikipedia:
The grant to Sandleford was confirmed by Edelina's daughter Beatrice de Fay (died before 1245), widow of Ralph de Fay, (she married secondly Hugh de Neville (died 1234)
Neville's first wife, Joan de Cornhill, died after December 1224. Some time before April 1230 he married secondly Beatrice, the widow of Ralph de Fay and one of the five daughters of Stephen of Turnham.
Eleanor (1307–1359), married firstly in 1319 with James of Aragon (the union was never consummated and annulled) and secondly in 1329 with King Alfonso IV of Aragon, brother of her first husband.
Edward of Norwich, 2nd Duke of York (c. 1373 – 25 October 1415), who married firstly, Beatrice of Portugal, which marriage was annulled, and secondly, Philippa Mohun, third daughter of John Mohun,
Isabella (1470–1498) married firstly to Afonso, Prince of Portugal, no issue. Married secondly to Manuel I of Portugal, no surviving issue.
John married secondly Constance of Castile in an attempt to win the throne of Castile that was unsuccessful.