Yes, so many famous names like Guinness, Usher, McEwan, Younger, etc etc not to mention the Dudgeon, Hunter, families etc.
One of my favourites is the old Fowlers brewery in Prestonpans. Exactly when Robert Fowler began brewing is only ever mentioned in passing – but 1745 is consistently given as the year. Fowlers's Wee Heavy is still a firm favourite of mine