Eva, I edited a profile as you suggested, with extensions disabled, to add an email address to the profile. On saving, I agree with what you said about the Suggestions visually dominates the box. I knew the message was there but visually, I think we go to the 'colored' Suggestion type and the 'white' box for the Comment. When there are more than one suggestion, as I had initially, there are more colors from multiple suggestions and comment boxes.
Jamie, maybe it would help if the Text was in bold Red when it is an Error that is preventing the Profile from being saved. The message is easier to see when there are no suggestions in the box.