Okay, first off.. the date should "probably" be 1850 and not 1820
Update: I think I have found the information.. look lower for the "Update"
So far, I haven't found information other than what you have... here is a screenshot from Ancestry http://imgur.com/RKQgBaH
Here is the same name from another location http://imgur.com/V9ARKy8
Here is proof that Wikitree works... you are already the third result for "Christopher Columbus Lowe" http://imgur.com/TafUnP1
Have you thought about looking for "Colombus" or other misspelligns?
Here's another CCL, but born 1894 http://www.genealogy.com/ftm/k/i/n/David-Kingsella/WEBSITE-0001/UHP-0037.html
This FindAGrave gives no help, but it is the couple you are referencing http://www.findagrave.com/cgi-bin/fg.cgi?page=gr&GRid=42260431
Here is the myheritage search for Christophere Lowe, and only one entry is for Missouri. http://www.myheritage.com/names/columbus_lowe
Here is a family history with MANY Christopher Columbus Lowes listed... although not a single one is from missouri. I would look at the line of this family naming as a clue to research http://hackerscreek.com/norman/LOWE/LEVI.htm
Okay, I may have found something REALLY interesting or Odd.... Look at the Green Hills Pioneers link here http://imgur.com/SR4IczG
from Google...They list the couple that you are looking for in the search... YET, there is no person of that name listed on the site: http://thegreenhills.org/Pioneers/b1228.htm
Personally, I would question the site owner if they removed that couple for a reason. Perhaps he found an error or renamed them something.
Here's another CCL, but doesn't seem to be yours http://imgur.com/TVDqa2d
Also, I would wonder if all of the CCL names have lineage to Christopher Columbus. I am not saying this simply because of the frequency but because of this article http://imgur.com/lOT1AF5
It seems someone named Lowe translated the Columbus journals around 1992. Very neat history link.
CCL from Florida born around 1890 http://imgur.com/Ip7aUpD
CCL from North Carolina http://imgur.com/1sKLPbN
UPDATE: I found a little more information on your couple using the correct birth http://imgur.com/fUUBvEa
Here is another Missouri CCL around the same time... different wife though http://imgur.com/2pIaUpc
I would suggest researching Barger's death date.
Here is another CCL from Tennesse with 3 wives http://imgur.com/bUdJvy1
I think this is the correct lineage!
Update: More supporting evidence found! http://imgur.com/5OBHhKT
Enjoy your search... those last two solidify it for me.