There are issues with the husband, as well as with the wife. He is said to be from two completely different places: (1) Alsace and (2) Simmental, Bern Canton, Switzerland. If they married in Europe, the theory on the wife would depend on which of these places he is thought to be from.
These are Palatine migrants. I added the husband's profile to the project. He is said to have sailed to Philadelphia on the ship Samuel in 1733. I have not looked up the ship records to find his arrival in Philadelphia and see whether the passenger record is one that listed family members in addition to adult men.
If they married in Europe and had children there before emigrating, the wife presumably came from the same area as the husband. The source for the Deshler-38 profile for the wife is a Pennsylvania county history volume that identifies her with a family whose patriarch had arrived in Pennsylvania in 1733. That suggests that somebody had a notion that they married in Pennsylvania in about 1733 -- and weren't necessarily from the same place. It is possible that this man had an earlier wife who died, and that Juliana Catharina was a younger woman whom he married after he arrived in America.
One of the arrival stories on his profile says he arrived in America with a wife and two young sons, but his profile is connected to profiles for several more children who were born in Europe between 1719 and 1733 and died in America. Not all of these "facts" can be true.