I can't say no one, but very few had middle names. If you see a profile with a middle name in the Middle Ages, it's probably a mistake.
In Wales or the West Midlands, people might be called John ap Morgan ap Thomas or John Morgan Thomas. It looks like a middle name but it's a patronymic. Also, in Medieval records, you might see some called Thomas Carter Smith, which is actually Thomas Carter, smith. In England, anyway, middle names didn't become usual until the 18th or 19th century.