Welcome to WikiTree.
Absolutely yes. I often do that as part of surname projects where I am trying to tie together different people with the same surname to see if I can eventually connect them to me eventually. Also, many people here take on famous groups of people, such as Presidents of the USA, that I would assume many are not directly connected to.
Please cite your sources and be careful about entering duplicates. WikiTree is usually pretty good about identiify duplicates unless there are different spellings of the last name.