The Shanghai ghetto was the setting for one of those remarkable tales of human ingenuity and survival.
Eva and Victor Saxl were a wealthy Jewish couple who escaped from Czechoslovakia, to Shanghai. Whilst there, Eva developed type 1 diabetes and to start with it was no problem as insulin was readily available. Supplies however eventually dried up, even on the black market , T1 diabetics cannot live without it.
With the help of a medical text book and a borrowed laboratory they experimented and taught themselves to make their own insulin from Water Buffalo pancreases. It was nothing like the clear insulin normally used, It was a murky brown substance and had a high risk of being contaminated. With some trepidation they tested it on Eva and it worked.
They went into production, making insulin not just for Eva but for over 400 people, supplying each without about 16 units a day and allowing them to survive.
short video here http://www.dlife.com/dlifetv/video/eva-saxl-a-love-story-part-1-