This is the only census I could find them in, no other marriage/death etc. Source: "United States Census, 1860", database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:MX51-3DD : 30 December 2015), Lawrence Donahue, 1860.
Lawrence Donahue M 34 Ireland Stone mason
Margaret Donahue F 33 Ireland
Catharine Donahue F 10 Pennsylvania
Lawrence Donahue M 7 Pennsylvania
John Donahue M 5 Pennsylvania
Michl Donahue M 3 Pennsylvania
Maggie Donahue F 1 Pennsylvania
John Power M 64 Ireland
Might this be his sister Anne? Do you know her married name?
Source: "Pennsylvania, Philadelphia City Death Certificates, 1803-1915," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:JDP4-G6Y : 9 December 2014), John Donahue in entry for Ann Byrnes, 27 Oct 1906; citing cn 26549, Philadelphia City Archives and Historical Society of Pennsylvania, Philadelphia; FHL microfilm 1,319,472.
Name Ann Byrnes
Death 27 Oct 1906 Philadelphia, Philadelphia, Pennsylvania
Female White Married
Age 78 Birth Date 20 Jul 1828 Birthplace Ireland
Father John Donahue Birthplace Ireland
Mother Ellen Kane Birthplace Ireland
Address Rear 2530 Buttonwood St, 15th Ward, Philadelphia, Philadelphia, PA
Burial 30 Oct 1906 Moorestown, Burlington Co., N.J.
Burial Date 30 Oct 1906