Question

How could Anne have been born in Jamestown before it was founded?

Answer 1

I would think that Jamestown could have been a setlement or unincorporated area before it was fomally  "founded" or incorporated. Another thought is that it could be a different Jamestown.

Answer 2

Anne being b in 1595 could not have been b in Jamestown, Va.  Jamestown was the first perminent colony in VA populated and  established in 1607.  Twelve years after her birth, There was a previous group that settled that area but they disappeared.  Some say they assimilated into the Native American Villages but that has not been proven.  Anyway it is obvious Anne was b in England.

Comments

http://www.coveytrees.com/SpencerTree explains that these are the wife and children of a different William Spencer.  

According to other sources, Anne was born in 1628

Answer 3

Anne would have had to have been a native.   Although not impossible, it is improbable.