I'm not sure if it is your grandparents or not. But the place is right, the names are right, and the year seems reasonable, so it could be them. It all starts with a theory. IF it is them and If they were part of a group that attracts this kind of scholarly study, then you may learnmore about them and their families by digging into some of those sources.
Each section of the document has references including land records, depositions, books, journals and articles related to the Cherokee.