As you didn't give much detail on years of birth etc I did a search (familysearch.org/records)with out dates on John Vowell Hooker and spouse as Alice Powell and found a number of John Hookers married to an Alice (no surname shown) with children - not siblings as birth years way too far apart, as follows:
Child Anne Hooker born 1569 in Compton, Sussex
Child Job Hooker born 1873 in Lancashire
Child john born 1639 in Hampshire
There are a whole lot more - maybe some would ring a bell