I have come around to doing it by default, mostly to use as a whiteboard. My standard template is BIography, Timeline, Research Notes, Sources. Biography, I typically only use for millitary service, occupation, or exceptional achievements. Also, for excerpts of published bios or obits with a lengthy discourse about their life. Timeline gets all the facts, Research Notes gets any conflicts, concerns, questionable data, and acts as a things to do list. It also doubles as a See Also for sources that are interesting but not used for whatever reason. I wish there were a way to separate the references visually though.
I work on profiles pretty much at random, so a notes section is valuable to keep track of where you are in relation to the spider web of their familial links. If you are working off a census, you may get parent's birthplaces, children, siblings, and other extended family right off the bat. That all goes into Research Notes until I have time or inclination to create their profiles.Many times I have moved on but someone following up will know immediately where to start if they want to add more detail.
Until I know a woman's LNAB, her information or at least links will go in the Research Notes of the spouse or eldest child. At least the info is close at hand for anyone interested in the immediate family. After typing it out a few times, Notes is looking better, easier on the eyes and fingers.
is an example of what I use it for.