How to prove mother of Ann Humphrey (Elizabeth or Susan) through DNA

+4 votes
There is an ongoing debate about the mother of Ann Humphrey (1625-1695). John Humphrey, Ann's father was married to two women - Elizabeth Pelham and Susan Fiennes Clinton. I have seen websites claiming both as Ann's mother. What is the most efficient way/place to find known relatives of Elizabeth Pelham to confirm or deny her parentage? I have done DNA testing but not sure how accurate it is to relatives born in 1625.
WikiTree profile: Anne Myles
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