Hi,
I don't think so looking at her parents and childrens names - but ... maybe. Here are a few details:
Maiden name: Horn or Horne
Born: 1725 Surrey, North Carolina. Died: 1797 Wake, NC,
Parents: William Horne (1660 - 1698) and Sarah Horne (b. Franklin) (1678 - 1731).
Children:
Isaac Holyfield (1740 - 1777)
William Holeyfield (1745 - 1820)
Daniel Holyfield (1753 - 1834)
Valentine Holyfield (1756 - 1820)
Oliver Holifield (1760 - 1802)
Regards,
Kevin