Are you familiar with the Sayre source material?
The profile's Biography probably does not list her as mother because the older book, by Banta does not have that information. Usually on the internet, people use the Banta material. Jacobus and Coddington covered that in several TAG articles. I'd have to go through it all to see what the points were, from them. (Obviously anyone with an American Ancestors sub can do this.) In my own personal database I have them connected with a caveat. It's been a long time since I looked at it since it's not my favorite area of research.
(I am a descendant of that John Wheeler and supposedly Alice, then the son John Wheeler who married Elizabeth.)