Just my thoughts:
That article says that only about 25 people in the world are known to have the condition. If that data is anywhere near accurate, the odds of running into the situation (abt 25 in 100 million? = 0.000025 per cent), are so slim that "Don't worry about!" is likely a good answer to your question. That doesn't account for unknown occurrences in past generations, of course, but with only 64 ancestors in 6 generations, the odds are something like 1 in 16 million of anyone having a problem.
Beyond 6 generations, things get pretty "iffy" in any case.
You would also need to take into account the probability that, in any particular family tree, other genealogical research (which has to accompany genetic genealogy at present) yields NO information on a particular individual.