If the potential merges are from very tangled relationships, it helps to go slowly. The potential duplicates become more clear when some of them are out of the way.
In your situation, they may be more clear, such as quite a few siblings who need to be merged. I would go ahead and do that if they are clear with same parents, same birth, etc. Watch out for names and birthdates as some families reused names, especially if the earlier child died young, especially in Quebec.
Also if the other profile manager(s) are active, you might want to send them a note to explain why these merges are coming their way. BTW I don't find it much work to do a merge if the data are clear. Be sure to add some notes to your merge proposal if something needs explanation.