This is a real tongue in cheek one but my fourth great grandparents were married in St. Kitts in 1797.
In the mid 1700s
her grandmother had a bar in Alexandria which had a GW room where George Washington regularly attended, as well as house parties at their mansion.
his step grandmother lived in the Kremlin, as wife of her first husband the General-in-Chief of the Russian army and Governor of Moscow (they are both buried with my family in Strutleln, Latvia) - his brother was Prince Regent.
I dont think they knew each other - I hope not lol - but given that his fourth cousins at the same time included the most beloved and longest reigning Queen of France, Marie wife of Louis XV and the morgantic spouse of Frederick Wilhelm - I think we could put together a historical fiction blockbuster - that well predates our current debacle