Wow, what a can of worms I opened when I started investigating a purported cousin link between my family and the family of President Bill Clinton (aka Blythe). It appears that there are three men, all of the same generation, born within 50 miles of each other (two in the same town) - all with the name Samuel Ayer. All three are grandsons of John Ayer-35. One was born in 1654 (Ayer-287), one in 1667 (no profile here yet) and the third in 1669 (Ayer-776).
This book does a pretty good job of listing out the families: http://books.google.com/books?id=D1BmAAAAMAAJ&pg=PA1184#v=onepage&q&f=false; The History of the Treman, Tremaine, Truman Family in America: With the Related Families of Mack, Dey, Board and Ayers; Ebenezer Mack Treman
But even this book makes a mistake and lists the wife of Ayer-287 as Elizabeth Tuttle (page 1181), when she was actually the wife of Ayer-776 (Ayer-287 married Mary Johnson, which the book states correctly on page 1171).
One of these three Samuels is the ancestor of President Clinton. I believe that to be the Samuel born in 1667, son of Obadiah Ayer, who settled in Woodbridge, New Jersey. However, online trees have had a heck of a time with these three men, compicated by the fact that the two Samuels closest together in age both married women named Elizabeth. I've found trees on both Ancestry and Geni.com that indicate Ayer-776 as the ancestor of President Clinton and I'm pretty certain now that that's not the case.
I'm still working through all this, but I'm going to place a cautionary note on all the profiles in question linking back to this discussion. Whew!