The Edmond Lewes line is well documented from Ipswich, Suffolk, England to Watertwown and Lynn, Massachusetts, and from there on to myself. See [[Lewes-85|Edmond Lewes]] for the full documentation.
As I explain in the Edmond Lewes biography, and in my book Descendants of Edmond Lewes of Lynn, Massachusetts, there were many Lewis/Lewes familes that came to North America during the Great Migration, from east Anglia, the Midlands, southern England and Wales. The Lewis/Lewes/Lowys surname was common in England in the 16th and 17th Centuries.
Teasing apart all these Lewis lines takes a great deal of research in the surviving documents. DNA research now helps to verify the documentation and provide direction for research where the documents are missing or not yet found.
Good luck in your Lewis research!