How do I upload Mt full sequence data from FTDNA to Wikitree?

+1 vote
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in WikiTree Help by Gale Watkins G2G1 (1.8k points)
retagged by Steve Schmidt

2 Answers

+6 votes
 
Best answer

Hi Gale,

Wikitree doesn't hold the actual dna itself just a record of where you took the dna. You can add the test information for your test you taken here: https://www.wikitree.com/wiki/Special:DNATests

For extra information how wikitree can help you with your dna read https://www.wikitree.com/wiki/Help:How_to_Get_Started_with_DNA

For places to upload I would suggest Gedmatch. May give you more hits than Family Tree.

by Steve Schmidt G2G6 Pilot (356k points)
selected by Dennis Wheeler
+3 votes
I'm not sure that the mtDNA raw data can be uploaded anywhere else outside of FT DNA.

GEDmatch will accept auDNA but I don't think they accept mtDNA or Y-DNA
by Robynne Lozier G2G6 Pilot (706k points)

I uploaded my full sequence mtDNA raw data results from FTDNA to GenBank. It is now public and can be compared to other sequences at GenBank using the NIH BLAST tool.  Other FTDNA customers have also uploaded their FMS to GenBank. This discussion thread at GenealogyWise.com describes a bit more about the process. I haven't heard of anyone doing this lately, so I can't confirm for certain that it is still possible.

Yes, Mardon; people certainly can submit their FTDNA FMS (full mitochondrial sequence) to GenBank. Thanks for pointing this out! yes

Here are instructions from Dr. Ian Logan:
http://www.ianlogan.co.uk/submission.htm

In fact, Ian responded to a question of mine yesterday and noted that there currently are 46,234 complete mtDNA sequences in the GenBank database, and 154,965 FMS results at FTDNA. Most GenBank uploads are from researchers and physicians, but everyone would benefit from more raw data by having a greater number of those FTDNA results uploaded to GenBank.

Wow! It's interesting that FTDNA has three times as many human Full Mitochondrial Sequences as GenBank. I didn't know that. Thanks, Edison, for sharing. Do you know how many of the mtDNA human genomes at GenBank were sequenced by FTDNA and uploaded by FTDNA customers?  That would be an interesting number.

I guess one thing that people should understand about GenBank is that it publicly shares the exact composition of the genome that is uploaded. None of the Direct To Consumer testing companies publicly publish what nucleotide bases occur at each locus that they test. GenBank intentionally does this. GenBank goes out of its way, however, to prevent anyone from linking the genomes they publish to the names of the individual person associated with each genome. If you look at my genome on GenBank, you will see that I am listed as one of the two "authors". This is very unusual. The other author is "Greenspan, B." because of his executive position at FTDNA where the sequencing was done.  It took a lot of additional correspondence from me to GenBank before they would agree to include my name as an author. They were very careful to make certain that I understood the potential future issues that might arise from this decision. People uploading to GenBank should understand that their upload may help scientific research but they should not expect to connect with relatives like happens on a normal DTC site.

I differed by one location from JQ703838.1, about 12 from rCRS, before I entered mine into GenBank.  Have you used PhyloTree.org to compare yours?  Still trying to learn how many folks test above L3 compared with number going M vs. N.  Just giving the few changes from common places like rCRS or main haplogroups may be easier.

Mardon, I don't know explicitly how to determine the number of mtDNA full-sequences uploaded to GenBank by FTDNA users, but I tried two different searches, one based on your post, to see if I could find how many FMS uploads came from FTDNA data.

Search #1 was: mitochondrion "homo sapiens" ftdna "complete genome"
It returned 2,031 hits.

Search #2 was: mitochondrion "homo sapiens" greenspan "complete genome"
It returned 3,029 hits.

I don't know if either of them are correct. I'll ask Ian in the near future if there's a better way to search. But if I had to guess, I'd say that the 3,000 number probably is a realistic top-end so far for kits originating from FTDNA. Makes sense because GenBank has no relatedness matching service, and I would imagine that only a small minority of people buying an FMS test as a consumer ever bother looking into GenBank.

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