Hi Jerie,
I'm not sure if anyone is working generally on the descendants of the signers of the US Declaration of Independence. That said, some of the signers would go on to become US Presidents, either under the Articles of Confederation or the US Constitution. I know that the US Presidents project does work on families (including some descendants, at least through grandchildren) of those individuals. See this page for more information on that project.
Greg, I found a category that is working on the signers of the Declaration of Independence. I think that would be the best place for you to start.
Hope that helps. Here is the link.
https://www.wikitree.com/wiki/Category:American_Founding_Fathers