As someone else said
First, STRs are helpful in the sense of "getting into the right ballpark", but they are too unstable to be highly reliable for determining who actually is the closest relative on the line of descent. We need SNPs for that.
If people want to ascertain where their line of descent is from, where their surname Patriarch ancestor was likely to have lived, and to which branch of their family they belong, they need to follow the SNP trail, not the STR trail.
These are SNPS and all Nesbit(t)s with the BY3373 mutation share an ancestor with Moses. (probably around end of 1500s)
But only Moses. and his descendants so far have R-BY43488 that either occurred with Moses are in one of his ancestors before the shared ancestor that had the BY3373 mutation. As Moses was born about 1740 we now then that R-BY43488 mutation occurred sometime 1740 or earlier and probably after end of 1500's.
So both SNPs are very important to the line as both are within a genealogy time frame and not hundreds of years ago like most SNPS. Both define one of Mose's ancestors that he shares with others.
In my opinion STR are seldom helpful in a genealogy time frame, but it does happen. I do have an example you can see on the category page I showed the link for above. It also shows the SNP tree