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I’ve had three breakthroughs using Thrulines, although when I say breakthrough really if I was diligent and smart enough I could have worked it out without being pointed there by Thrulines.
I’m defining breakthrough as extending back a generation or more, or finding a whole bunch of siblings to an ancestor I hadn’t known about.
Three breakthroughs is far smaller than the number of dodgy leads I’ve had. The big problem is the “possible ancestor” suggestions that actually have no DNA basis, they’re just in a DNA relatives tree, farther back than the connection actually is.
Where I’ve found it most useful is where I’ve been unable to trace a sibling or nephew, and their DNA descendants tree matches up to mine. Nine times out of ten the paper trail is very strong and I metaphorically slap my forehead for not finding it in the first place.
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Also Thrulines helps you work around private trees. It won’t show you the private person but will show you the exact same person in someone else’s tree.